1-(2-Nitrophenyl)-1,2,4-triazole CAS 25688-22-6
| CAS No. | 25688-22-6 |
| Molecular Formula | C8H6N4O2 |
| Molecular Weight | 190.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2-Nitrophenyl)-1,2,4-triazole is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2-Nitrophenyl)-1,2,4-triazole (CAS 25688-22-6), molecular formula C8H6N4O2 and molecular weight 190.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Nitrophenyl)-1,2,4-triazole (C8H6N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-Nitrophenyl)-1,2,4-triazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6N4O2 |
| Molecular Weight | 190.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 4 |
Related Nitrophenyl Standards
- 5-(4-Nitrophenyl)oxazole (CAS 1014-23-9)
- 4-(2-Nitrophenyl)oxazole (CAS 1126636-34-7)
- 1-(4-Nitrophenyl)-1,2,3-triazole (CAS 1204-91-7)
- 5-(3-Nitrophenyl)-1,2-oxazole (CAS 126633-02-1)
- 4-(4-Nitrophenyl)oxazole (CAS 13382-61-1)
- 4-(4-Nitrophenyl)-4H-1,2,4-triazole (CAS 16759-47-0)
- 4-(4-Nitrophenyl)isoxazole (CAS 17819-23-7)
- 2-(4-Nitrophenyl)-2H-1,2,3-triazole (CAS 18922-72-0)
Recommended Standards
- 1-(1,3-Benzodioxol-5-yl)-1H-tetrazole (CAS 326874-59-3)
- 1-(3-(Difluoromethyl)-2-fluorophenyl)ethanol (CAS 2159920-60-0)
- [4,5'-Bipyrimidine]-4',6(1H,3'H)-dione (CAS 59549-39-2)
- 1-(3-Nitrophenyl)-1H-1,2,4-triazole (CAS 25688-23-7)
- 2-(propan-2-yl)-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one (CAS 2060058-22-0)
- n-Methyl-1-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)methanamine 2,2,2-trifluoroacetate (CAS 1255717-28-2)
- 4-(3-Nitrophenyl)-1,2,3-thiadiazole-5-carboxylic acid (CAS 1481665-11-5)
- N-Methyl-1-(4-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)methanamine (CAS 884507-32-8)
- 5-bromo-1-(propan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,2,3-triazole (CAS 2364586-27-4)
- 1-(2-Bromo-1-fluoroethyl)-4-methylbenzene (CAS 66472-41-1)
- 5-((5-Ethylfuran-2-yl)methyl)-1H-imidazole (CAS 226571-41-1)
- 2-(2-Chloro-3-methylpyridin-4-yl)acetonitrile (CAS 1227581-37-4)
- N-Cyclohexyl-2,2-diphenylacetamide (CAS 24932-56-7)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com