6-chloro-1H-indole-5-carboxylic acid CAS 256935-86-1
| CAS No. | 256935-86-1 |
| Molecular Formula | C9H14ClNO2 |
| Molecular Weight | 203.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-chloro-1H-indole-5-carboxylic acid.
CATO supplies 6-chloro-1H-indole-5-carboxylic acid (CAS 256935-86-1), a certified reference material (molecular formula C9H14ClNO2, MW 203.67 g/mol) for analytical method development and quality control.
The molecular framework of 6-chloro-1H-indole-5-carboxylic acid (C9H14ClNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-chloro-1H-indole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H14ClNO2 |
| Molecular Weight | 203.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 3-Chloro-N-phenylaniline (CAS 101-17-7)
- 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde (CAS 1111237-78-5)
- 2-Chloro-4-(4-methylphenyl)pyridine (CAS 1202574-24-0)
- 2'-Chloro-[1,1'-biphenyl]-2-amine (CAS 1203-43-6)
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- 2-Chloro-4-methyl-5-phenylpyridine (CAS 1214335-53-1)
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Recommended Standards
- 6-Chloro-[1,1'-biphenyl]-3-amine (CAS 56970-25-3)
- 7-chloro-1H-indole-4-carboxylic acid (CAS 588688-45-3)
- 6-Chloro-[1,1'-biphenyl]-2-amine (CAS 76838-85-2)
- 7-chloro-4-methyl-2H-pyrido[3,4-d]pyridazin-1-one (CAS 2654746-75-3)
- 1-(3-Bromophenyl)-1H-pyrazole-4-carbonitrile (CAS 1208081-18-8)
- 5-Fluoro-3-methylpyrimidin-4(3H)-one (CAS 347418-38-6)
- 2-(Cyclohex-1-en-1-yl)-2-methylpropanenitrile (CAS 54353-80-9)
- ethyl 2-(3-aminobicyclo[1.1.1]pentan-1-yl)acetate hydrochloride (CAS 2096992-03-7)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-methoxyphenyl)methanone (CAS 898761-44-9)
- Benzo[d]oxazole-6-carbaldehyde (CAS 865449-97-4)
- 3-Methoxy-N-(4-methylpiperidin-3-yl)propanamide (CAS 1832043-55-6)
- 3-(4-Isobutylphenyl)-1-phenyl-1H-pyrazole-5-carboxylic acid (CAS 618102-88-8)
- 2-(Difluoromethyl)nicotinaldehyde (CAS 1211532-98-7)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
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