6-Chloro-N-isopropyl-5-nitropyrimidin-4-amine CAS 25710-25-2
| CAS No. | 25710-25-2 |
| Molecular Formula | C7H9ClN4O2 |
| Molecular Weight | 216.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-N-isopropyl-5-nitropyrimidin-4-amine.
6-Chloro-N-isopropyl-5-nitropyrimidin-4-amine (CAS 25710-25-2) is a high-purity analytical reference standard with the molecular formula C7H9ClN4O2 and a molecular weight of 216.62 g/mol.
The molecular framework of 6-Chloro-N-isopropyl-5-nitropyrimidin-4-amine (C7H9ClN4O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-N-isopropyl-5-nitropyrimidin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H9ClN4O2 |
| Molecular Weight | 216.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- Ethyl 6-chloro-3-hydrazinylpyridazine-4-carboxylate (CAS 1073488-86-4)
- 2-(4-Chloro-2-nitrophenoxy)ethan-1-amine (CAS 1183594-44-6)
- Ethyl 3-chloro-2-oxopyrazine-1(2H)-carboxylate (CAS 1194374-11-2)
- Ethyl 2-(5-chloro-1-methyl-1h-imidazol-2-yl)-2-oxoacetate (CAS 1210133-00-8)
- 3-(3-Chloro-4-hydroxyphenyl)-3-hydroxypropanoic acid (CAS 1248246-33-4)
- 2-(5-Chloro-2-nitrophenoxy)ethan-1-amine (CAS 1248814-38-1)
- 2-(3-Chloro-4-nitrophenoxy)ethan-1-amine (CAS 1249187-43-6)
- 2-Chloro-6-(methoxymethoxy)benzoic acid (CAS 1253188-17-8)
Recommended Standards
- 6-Chloro-5-nitro-N-propylpyrimidin-4-amine (CAS 326831-74-7)
- 8-Chloro-6-(1,1-difluoroethyl)imidazo[1,2-a]pyridine (CAS 2747919-24-8)
- 5-Chloro-3-nitro-2-propoxypyridine (CAS 886373-37-1)
- Ethyl 2-(3-chloro-2-oxopyrazin-1(2H)-yl)acetate (CAS 435345-05-4)
- Boc-arg(mbS)-oh (CAS 58810-09-6)
- 3-(3,5-Dimethylbenzenesulfonyl)-6,7-difluoro-1-propyl-1,4-dihydroquinolin-4-one (CAS 1547050-53-2)
- (2S,5R)-5-Isopropylpyrrolidine-2-carboxylic acid (CAS 110452-55-6)
- Difelikefalin Impurity 10 (CAS 2756592-19-3)
- (S)-4-(1-amino-2,2,2-trifluoroethyl)phenol (CAS 1187930-88-6)
- 4-(Thiophen-3-yl)butan-2-one (CAS 65857-53-6)
- 5-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-chloronicotinic acid (CAS 2243514-88-5)
- 4-(Benzyloxy)-3-bromophenylacetic Acid (CAS 5884-48-0)
- 2,6-Bis[(4R,5R)-4,5-dihydro-1-[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1H-imidazol-2-yl]pyridine (CAS 863491-57-0)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
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