3-[3,5-di(trifluoromethyl)phenyl]-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)prop-2-en-1-one CAS 257284-94-9
| CAS No. | 257284-94-9 |
| Molecular Formula | C21H13F6NOS |
| Molecular Weight | 441.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-[3,5-di(trifluoromethyl)phenyl]-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)prop-2-en-1-one (CAS 257284-94-9) is a high-purity analytical reference standard with the molecular formula C21H13F6NOS and a molecular weight of 441.39 g/mol.
The molecular framework of 3-[3,5-di(trifluoromethyl)phenyl]-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)prop-2-en-1-one (C21H13F6NOS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H13F6NOS |
| Molecular Weight | 441.39 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related di Standards
- 3-(Trifluoromethyl)-N-(4-((3-(trifluoromethyl)phenyl)thio)phenyl)benzamide (CAS 339104-72-2)
- 4-{[1-methyl-3-(trifluoromethyl)-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]methoxy}benzonitrile (CAS 318959-27-2)
- 1-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-4-(4-fluorophenyl)-1H-pyrazol-5-amine (CAS 321522-23-0)
- 4-{5-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}-1-(2,4,6-trimethylbenzoyl)piperidine (CAS 1030386-13-0)
- 3-[3,5-di(trifluoromethyl)phenyl]prop-2-ynyl N-(1,2,2-trichlorovinyl)carbamate (CAS 646989-49-3)
- 4-[Bis[4-(trifluoromethyl)phenyl]phosphino]benzoic Acid (CAS 1808959-36-5)
- 3-(Trifluoromethyl)-N-(4-(2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)phenyl)benzamide (CAS 1024231-00-2)
- 7-Benzyl-4-(4-(trifluoromethyl)benzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one (CAS 1807861-48-8)
Recommended Standards
- 4,4′,4″-((1,3,5-Triazine-2,4,6-triyl)tris(oxy))tribenzaldehyde (CAS 3140-75-8)
- 4'-(4-Carboxyphenyl)-[2,2':6',2"-terpyridine]-5,5"-dicarboxylic acid (CAS 1887067-79-9)
- 4,4''-Dinitro-5'-(4-nitrophenyl)-1,1':3',1''-terphenyl (CAS 29102-61-2)
- Phenyleneethylenetriamine Pentaacetic Acid (CAS 126736-75-2)
- 2-(4-Ethoxyphenyl)-5-(p-tolyl)-1,3,4-oxadiazole (CAS 338426-44-1)
- (2S,5S)-5-phenylpyrrolidine-2-carboxylic acid (CAS 917615-20-4)
- 1-(4-Chlorophenyl)-1,5-dihydro-4-(1-piperidinyl)-2H-imidazol-2-one (CAS 188116-08-7)
- Phosphorylase Kinase β-Subunit Fragment (420-436) (CAS 150829-21-3)
- 2-chloro-N-{2-[(dimethylamino)sulfonyl]benzyl}acetamide (CAS 1110909-17-5)
- 4-Benzyl-2-(chloromethyl)-6-methylmorpholine (CAS 40987-50-6)
- 4-(4-Bromophenethoxy)benzaldehyde (CAS 955931-76-7)
- 1-(Tert-butoxycarbonyl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-5'-carboxylic acid (CAS 2306272-31-9)
- Enzalutamide Impurity 52 (CAS CATO-C4X-101652)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com