(R)-4,4,5,5-Tetramethyl-2-(1-(p-tolyl)ethyl)-1,3,2-dioxaborolane CAS 257298-94-5

Purity 97%+In StockPharmaceutical Standards
CAS No.257298-94-5
Molecular FormulaC15H23BO2
Molecular Weight246.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-4,4,5,5-Tetramethyl-2-(1-(p-tolyl)ethyl)-1,3,2-dioxaborolane CAS 257298-94-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-4,4,5,5-Tetramethyl-2-(1-(p-tolyl)ethyl)-1,3,2-dioxaborolane.

(R)-4,4,5,5-Tetramethyl-2-(1-(p-tolyl)ethyl)-1,3,2-dioxaborolane (CAS 257298-94-5), molecular formula C15H23BO2 and molecular weight 246.15 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, (R)-4,4,5,5-Tetramethyl-2-(1-(p-tolyl)ethyl)-1,3,2-dioxaborolane (C15H23BO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.5, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 246.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H23BO2
Molecular Weight246.15 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025

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