4-Chloro-6-iodo-2-phenylquinazoline CAS 257624-25-2

Purity 97%+In StockPharmaceutical Standards
CAS No.257624-25-2
Molecular FormulaC14H8ClIN2
Molecular Weight366.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-6-iodo-2-phenylquinazoline CAS 257624-25-2 chemical structure

Description

The occurrence of 4-Chloro-6-iodo-2-phenylquinazoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Chloro-6-iodo-2-phenylquinazoline (CAS 257624-25-2) is a high-purity analytical reference standard with the molecular formula C14H8ClIN2 and a molecular weight of 366.58 g/mol.

Based on its molecular formula C14H8ClIN2, 4-Chloro-6-iodo-2-phenylquinazoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 366.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chloro-6-iodo-2-phenylquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H8ClIN2
Molecular Weight366.58 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl/I-containing
Nitrogen Atoms2

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