Methyl 5-fluoro-3-methylindoline-3-carboxylate CAS 2577447-91-5

Purity 97%+In StockPharmaceutical Standards
CAS No.2577447-91-5
Molecular FormulaC11H12FNO2
Molecular Weight209.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 5-fluoro-3-methylindoline-3-carboxylate CAS 2577447-91-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 209.22 g/mol gives Methyl 5-fluoro-3-methylindoline-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Methyl 5-fluoro-3-methylindoline-3-carboxylate (CAS 2577447-91-5), molecular formula C11H12FNO2 and molecular weight 209.22 g/mol, is a CATO reference standard with documented purity and traceability.

Methyl 5-fluoro-3-methylindoline-3-carboxylate (C11H12FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Methyl 5-fluoro-3-methylindoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H12FNO2
Molecular Weight209.22 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2001
Halogen ContentF-containing
Nitrogen Atoms1

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