Epinephrine /Adrenaline Impurity 128 CAS 25775-86-4

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.25775-86-4
Molecular FormulaC9H11N3O6
Molecular Weight257.20 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Epinephrine /Adrenaline Impurity 128 CAS 25775-86-4 chemical structure

Description

The occurrence of Epinephrine /Adrenaline Impurity 128 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Epinephrine /Adrenaline Impurity 128 (CAS 25775-86-4), a pharmacopoeial impurity reference standard (molecular formula C9H11N3O6, MW 257.20 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Epinephrine /Adrenaline Impurity 128 (C9H11N3O6) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 257.20 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H11N3O6
Molecular Weight257.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964
Nitrogen Atoms3

Related Epinephrine Standards

Recommended Standards

Why CATO?