3-(Dimethylamino)-5-(trifluoromethyl)picolinonitrile CAS 257862-49-0
| CAS No. | 257862-49-0 |
| Molecular Formula | C9H8F3N3 |
| Molecular Weight | 215.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(Dimethylamino)-5-(trifluoromethyl)picolinonitrile (CAS 257862-49-0) is a high-purity analytical reference standard with the molecular formula C9H8F3N3 and a molecular weight of 215.18 g/mol.
3-(Dimethylamino)-5-(trifluoromethyl)picolinonitrile (C9H8F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(Dimethylamino)-5-(trifluoromethyl)picolinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8F3N3 |
| Molecular Weight | 215.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dimethylamino Standards
- 6-(Dimethylamino)-4-(trifluoromethyl)picolinonitrile (CAS 1431555-30-4)
- 2-(Dimethylamino)-6-(trifluoromethyl)nicotinonitrile (CAS 935518-01-7)
- ((Dimethylamino)(phenyl)methyl)phosphonic acid (CAS 67623-08-9)
- 2-(4-(Dimethylamino)phenyl)-2,2-difluoroacetic acid (CAS 1249245-53-1)
- 2-(Dimethylamino)-4-phenylpyrimidin-5-ol (CAS 107361-61-5)
- (E)-3-(Dimethylamino)-1-(3-imidazo[1,2-a]pyridyl)-2-propen-1-one (CAS 878804-63-8)
- 2-(Dimethylamino)-5-phenylpyrimidin-4(1H)-one (CAS 65942-56-5)
- 3-(Dimethylamino)-6-phenylpyridazin-4-ol (CAS 89868-15-5)
Recommended Standards
- 2-Fluoro-1-(2-methoxyethoxy)-4-nitrobenzene (CAS 221198-59-0)
- 3-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzenemethanamine (CAS 870562-47-3)
- 2,2-Difluoro-5-isothiocyanatobenzo[d][1,3]dioxole (CAS 869085-97-2)
- 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzenemethanamine (CAS 400781-05-7)
- 6-(4-Methoxyphenyl)pyrimidin-4-ol (CAS 130841-04-2)
- Urocortin III (human) trifluoroacetate salt (CAS 357952-09-1)
- Praseodymium(III) bromide hydrate (CAS 225505-12-4)
- 5,6-Dichloro-2-(chloromethyl)-1H-benzo[d]imidazole (CAS 39811-03-5)
- 6,7-Dimethoxy-1,4-phthalazinediol (CAS 10001-35-1)
- (3-(Azetidin-3-yloxy)phenyl)methanol (CAS 1339721-51-5)
- 1-(2-(sec-Butylamino)-1H-imidazol-4-yl)ethanone (CAS 88723-22-2)
- 4,6-Difluoroisatin (CAS 126674-93-9)
- N-(2,2-dimethyl-4-oxochroman-6-yl)acetamide (CAS 186774-61-8)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com