3-(1-(3-(1H-Imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione CAS 257879-35-9
| CAS No. | 257879-35-9 |
| Molecular Formula | C24H21N5O2 |
| Molecular Weight | 411.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-(1-(3-(1H-Imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione (CAS 257879-35-9) is a high-purity analytical reference standard with the molecular formula C24H21N5O2 and a molecular weight of 411.46 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 3-(1-(3-(1H-Imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 411.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H21N5O2 |
| Molecular Weight | 411.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
Related H Standards
- 3-(5-(4-(1H-Imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid (CAS 1208315-24-5)
- 1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one (CAS 350678-63-6)
- (4-((1H-Imidazol-1-yl)methyl)phenyl)(4-(5-(furan-2-yl)-1,3,4-thiadiazol-2-yl)piperidin-1-yl)methanone (CAS 1226456-65-0)
- (4-((1H-Imidazol-1-yl)methyl)phenyl)(3-(5-(thiophen-3-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone (CAS 1797579-24-8)
- 3-[3-(1H-Imidazol-1-yl)propyl]-6,7-dimethoxy-2-[(2-methylpropyl)sulfanyl]-3,4-dihydroquinazolin-4-imine (CAS 691870-01-6)
- 1-(3-(1h-Imidazol-1-yl)propyl)-4-benzoyl-3-hydroxy-5-(p-tolyl)-1,5-dihydro-2h-pyrrol-2-one (CAS 309270-92-6)
- 1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-chlorophenyl)-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one (CAS 381717-91-5)
- 1-(3-(1H-Imidazol-1-yl)propyl)-4-(furan-2-carbonyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 378212-42-1)
Recommended Standards
- 2,6-Dimethyl-3,5-Diethoxycarbonyl-4-(2-(Difluoromethylthio)Phenyl)-1,4 -Dihydropyridine (CAS 84761-73-9)
- 5-(4-((4-Methylbenzyl)oxy)phenyl)-N'-(pyridin-3-ylmethylene)-1H-pyrazole-3-carbohydrazide (CAS 634896-54-1)
- (4-Methylpiperazin-1-yl)(3-(thiophen-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)methanone (CAS 477845-20-8)
- Tofacitinib Impurity 163 (CAS CATO-C4X-1079163)
- 1-(2-Chloro-5-methoxyphenyl)piperazine (CAS 180698-24-2)
- 6-Fluoro-3-piperidin-4-yl-1H-indole hydrochloride (CAS 180411-84-1)
- Aminophylline (CAS 317-34-0)
- 8-fluoro-2,3,4,5-tetrahydro-1,4-benzoxazepine (CAS 844648-13-1)
- 1-(P-tolyl)-1H-pyrrole-2-carboxylic acid (CAS 35524-50-6)
- Tris(1-phenyl-1,3-butanediono)iron (CAS 14323-17-2)
- Methyl 2-oxo-1,2-dihydroquinoline-3-carboxylate (CAS 73776-17-7)
- 2-(Azepan-2-yl)cyclopentan-1-one (CAS 1514186-80-1)
- 874-10-2 8-methylimidazo[1,2-a]pyridine DTXSID60316598 (CAS 874-10-2)
- Glucagon (1-29) (CAS 16941-32-5)
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