2-Chloro-5-phenylpyrazine CAS 25844-73-9
| CAS No. | 25844-73-9 |
| Molecular Formula | C10H7ClN2 |
| Molecular Weight | 190.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Chloro-5-phenylpyrazine (CAS 25844-73-9), a certified reference material (molecular formula C10H7ClN2, MW 190.63 g/mol) for analytical method development and quality control.
2-Chloro-5-phenylpyrazine (C10H7ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5-phenylpyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2 |
| Molecular Weight | 190.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-3,3'-bipyridine (CAS 101001-94-9)
- 6-Chloro-1-naphthaldehyde (CAS 116632-02-1)
- 4-Chloro-7-methyl-1H-indole-6-carbonitrile (CAS 1167056-04-3)
- 2-Chloro-3,4'-bipyridine (CAS 1187968-06-4)
- 5-chloro-1-methyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS 1211533-31-1)
- 4-Chloro-2,4'-bipyridine (CAS 1214335-54-2)
- 2-Chloro-N'-(2-cyclopropylacetyl)acetohydrazide (CAS 1263386-34-0)
- 2-Chloro-4-phenylpyrimidine (CAS 13036-50-5)
Recommended Standards
- 2-Chloro-5-(pyridin-4-yl)pyridine (CAS 79739-22-3)
- 2-Chloro-5-phenylpyrimidine (CAS 22536-62-5)
- 2-Chloro-4,4’-bipyridine (CAS 53344-73-3)
- 2-Chloro-6-phenylpyrazine (CAS 41270-62-6)
- 1-Bromo-4-hydroxy-2-butanone (CAS 1138728-96-7)
- 5-Ethyl-2,4-dimethylaniline hydrochloride (CAS 1244949-51-6)
- N-cyclopentyl-2-(piperidin-4-yl)imidazo[1,2-a]pyridin-3-amine (CAS 1242964-50-6)
- Ticagrelor Impurity 35 (CAS CATO-C4X-109335)
- (2S,4S)-Ethyl 4-methylpyrrolidine-2-carboxylate (CAS 745769-71-5)
- (2E)-2-[2-(3,5-dimethylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one (CAS 744242-03-3)
- 4-(Propan-2-yl)-2-(pyrrolidin-2-yl)-1,3-oxazole dihydrochloride (CAS 2097897-75-9)
- 5-Chloro-4-nitro-2-(trifluoromethyl)phenol (CAS 2387068-52-0)
- 3-[4-(Benzyloxy)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 696649-46-4)
- Uremic Pentapeptide (CAS 71494-20-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com