4-(4-Fluorophenyl)-1-methylpiperidine-4-carbonitrile CAS 258500-80-0
| CAS No. | 258500-80-0 |
| Molecular Formula | C13H15FN2 |
| Molecular Weight | 218.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-Fluorophenyl)-1-methylpiperidine-4-carbonitrile (CAS 258500-80-0), molecular formula C13H15FN2 and molecular weight 218.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-Fluorophenyl)-1-methylpiperidine-4-carbonitrile (C13H15FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Fluorophenyl)-1-methylpiperidine-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H15FN2 |
| Molecular Weight | 218.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- (1-(3-Fluorophenyl)-2,5-dimethyl-1h-pyrrol-3-yl)methanamine (CAS 1177274-68-8)
- (1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methanamine (CAS 938121-25-6)
- 1-(4-Fluorophenyl)-4-(prop-2-yn-1-yl)piperazine (CAS 861206-49-7)
- 4-(2-Fluorophenyl)-1-methylpiperidine-4-carbonitrile (CAS 69584-88-9)
- 4-(3-Fluorophenyl)-1-methylpiperidine-4-carbonitrile (CAS 669069-13-0)
- (4-Fluorophenyl)(phenyl)methanethiol (CAS 1039319-73-7)
- N-[(3-fluorophenyl)methyl]-N-methylaminosulfonamide (CAS 1094315-37-3)
- 1223748-33-1 3-(4-fluorophenyl)propane-1-sulfonic acid 3-(4-fluorophenyl)propane-1-sulfonicacid A11451 (CAS 1223748-33-1)
Recommended Standards
- 4-(3-Methoxyphenyl)thiophene-2-carbaldehyde (CAS 893736-82-8)
- 4-Benzyl- 2-thiophenecarboxylic Acid (CAS 27921-49-9)
- 4-fluoro-1-(piperidin-3-yl)-1H-indole (CAS 2164095-77-4)
- 4-(2-Methoxyphenyl)-2-thiophenecarbaldehyde (CAS 893736-85-1)
- 2-Amino-n-tert-butylethane-1-sulfonamide hydrochloride (CAS 61300-17-2)
- 2-(3-Hydroxypyrrolidin-1-yl)acetonitrile (CAS 857637-01-5)
- 7-Methoxy-6-azaindole (CAS 160590-40-9)
- 4-(2-Ethyl-1-methyl-1H-imidazol-5-yl)pyrimidin-2-amine (CAS 403792-95-0)
- 5-(tert-Butoxycarbonyl)octahydrofuro[3,2-c]pyridine-7-carboxylic acid (CAS 1823406-41-2)
- N,2-Dimethyl-2-(methylamino)propanamide (CAS 88876-37-3)
- 3-((2-acetylphenoxy)methyl)-4-bromo-2-methyl-1-phenyl-3-pyrazolin-5-one (CAS 497061-10-6)
- 2-Hydroxy-5-(2-methylbutan-2-yl)benzaldehyde (CAS 63753-16-2)
- (S,R,S)-AHPC-acetamido-O-PEG2-C1-acid (CAS 2172820-10-7)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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