5-Fluorothiophen-2-amine CAS 258522-43-9

Description

The occurrence of 5-Fluorothiophen-2-amine is closely related to a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Fluorothiophen-2-amine (CAS 258522-43-9) is a high-purity analytical reference standard with the molecular formula C4H4FNS and a molecular weight of 117.14 g/mol.

Owing to a nitrile group, sulfur-containing functionality, fluorine substitution, 5-Fluorothiophen-2-amine is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 117.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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