1-(3-chlorophenyl)-3-methylenedihydro-1H-pyrrole-2,5-dione CAS 2593-51-3
| CAS No. | 2593-51-3 |
| Molecular Formula | C11H8ClNO2 |
| Molecular Weight | 221.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-chlorophenyl)-3-methylenedihydro-1H-pyrrole-2,5-dione (CAS 2593-51-3), molecular formula C11H8ClNO2 and molecular weight 221.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-chlorophenyl)-3-methylenedihydro-1H-pyrrole-2,5-dione (C11H8ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-chlorophenyl)-3-methylenedihydro-1H-pyrrole-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO2 |
| Molecular Weight | 221.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chlorophenyl Standards
- 5-(3-Chlorophenyl)-1h-pyrrole-2-carboxylic acid (CAS 1048917-65-2)
- 5-(2-Chlorophenyl)-1h-pyrrole-2-carboxylic acid (CAS 1048919-09-0)
- 3-(4-Chlorophenyl)-1H-pyrazole-4-carbaldehydeoxime (CAS 1199253-23-0)
- 5-(4-Chlorophenyl)-3-methylisoxazole-4-carbaldehyde (CAS 1208081-07-5)
- 5-(3-Chlorophenyl)-3-methylisoxazole-4-carbaldehyde (CAS 1208081-72-4)
- 4-(4-Chlorophenyl)-1H-pyrrole-3-carboxylic acid (CAS 122453-98-9)
- 3-(4-Chlorophenyl)-6-methyl-1,2,4-triazin-5(2H)-one (CAS 126542-93-6)
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Recommended Standards
- 1-(3-Chlorophenyl)-1H-pyrrole-2-carboxylic acid (CAS 952958-82-6)
- 1-(4-Chloro-6-methylpyrimidin-2-yl)-1H-pyrrole-2-carbaldehyde (CAS 881040-35-3)
- 1-(3-Chloro-2-methylphenyl)-1H-pyrrole-2,5-dione (CAS 58670-25-0)
- 1-(4-Chlorobenzyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 952183-30-1)
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- 1-Phenyl-3-(pyridin-2-ylmethyl)urea (CAS 53101-94-3)
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- (4-((6-(Trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanol (CAS 1086376-61-5)
- 4-(3,5-Dichloro-4-hydroxyphenyl)-4-oxobutanoic acid (CAS 62903-25-7)
- Des-Trp25-Tirzepatide (CAS CATO-CPTD788948)
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