tert-Butyl (3aS,6aR)-3,3-difluorohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate CAS 2597332-58-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2597332-58-4
Molecular FormulaC11H18F2N2O2
Molecular Weight248.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl (3aS,6aR)-3,3-difluorohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate CAS 2597332-58-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

tert-Butyl (3aS,6aR)-3,3-difluorohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate (CAS 2597332-58-4), molecular formula C11H18F2N2O2 and molecular weight 248.27 g/mol, is a CATO reference standard with documented purity and traceability.

tert-Butyl (3aS,6aR)-3,3-difluorohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate (C11H18F2N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), tert-Butyl (3aS,6aR)-3,3-difluorohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H18F2N2O2
Molecular Weight248.27 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2001
Halogen ContentF-containing
Nitrogen Atoms2

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