4-Bromopyrimidine-2-carboxylic acid CAS 259810-39-4
| CAS No. | 259810-39-4 |
| Molecular Formula | C5H3BrN2O2 |
| Molecular Weight | 202.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromopyrimidine-2-carboxylic acid (CAS 259810-39-4), molecular formula C5H3BrN2O2 and molecular weight 202.99 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromopyrimidine-2-carboxylic acid (C5H3BrN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Bromopyrimidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H3BrN2O2 |
| Molecular Weight | 202.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromopyrimidine Standards
- 2-Bromopyrimidine-4-carboxylic Acid (CAS 1211515-50-2)
- 2-Bromopyrimidine-5-carboxylic acid (CAS 1224885-47-5)
- 4-Bromopyrimidine-5-carboxylic acid (CAS 1522059-70-6)
- 6-Bromopyrimidine-4-carboxylic acid (CAS 1555494-28-4)
- 5-Bromopyrimidine-2-carboxylic Acid (CAS 37131-87-6)
- 6-Bromopyrimidine-4-carboxamide (CAS 1209458-24-1)
- 2-Bromopyrimidine-5-carboxamide (CAS 1209458-32-1)
- 2-Bromopyrimidine-4-carboxamide (CAS 1209458-85-4)
Recommended Standards
- 4-Bromo-3-nitropyridine (CAS 23056-44-2)
- 5-Bromo-2-pyrazinecarboxylic acid (CAS 876161-05-6)
- 3-Bromofuran-2,5-dicarbaldehyde (CAS 4805-99-6)
- 5-Bromo-4-pyrimidinecarboxylic Acid (CAS 64224-60-8)
- 4-(4-(Trifluoromethoxy)phenyl)pyrimidin-2-amine (CAS 874779-70-1)
- (5-(Ethoxymethyl)-2-methoxyphenyl)boronic acid (CAS 1334679-92-3)
- Diphenyl((phenylsulfinyl)methyl)phosphine oxide (CAS 87762-75-2)
- (E)-3-(dimethylamino)-1-phenylprop-2-en-1-one (CAS 1201-93-0)
- 5-Aminoquinolin-4-ol (CAS 13065-98-0)
- 5-(Trifluoromethyl)morpholine-3-thione (CAS 1354950-37-0)
- 3-Ethyl-6-methoxy-2-methylquinoline-4-thiol (CAS 332150-08-0)
- 1-tert-butyl-5-cyclopropyl-1H-pyrazole (CAS 1803581-27-2)
- (S)-2-Hydroxybutanoic acid (CAS 3347-90-8)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com