7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine CAS 26035-89-2

Purity 97%+In StockPharmaceutical Standards
CAS No.26035-89-2
Molecular FormulaC14H12ClN3
Molecular Weight257.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine CAS 26035-89-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine.

7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 26035-89-2), molecular formula C14H12ClN3 and molecular weight 257.72 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (C14H12ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H12ClN3
Molecular Weight257.72 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964
Halogen ContentCl-containing
Nitrogen Atoms3

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