(2-Chloropyridin-3-yl){4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}methanone CAS 260392-54-9
| CAS No. | 260392-54-9 |
| Molecular Formula | C16H14ClF3N4O |
| Molecular Weight | 370.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (2-Chloropyridin-3-yl){4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}methanone (C16H14ClF3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(2-Chloropyridin-3-yl){4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}methanone (CAS 260392-54-9) is a high-purity analytical reference standard with the molecular formula C16H14ClF3N4O and a molecular weight of 370.76 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2-Chloropyridin-3-yl){4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClF3N4O |
| Molecular Weight | 370.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloropyridin Standards
- 3-[(1Z)-1-[2-(6-Chloropyridin-2-yl)hydrazin-1-yl]-2-(1H-1,2,4-triazol-1-yl)ethylidene]-1-phenylurea (CAS 338418-61-4)
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Recommended Standards
- N-(2-Chloro-5-(trifluoromethyl)phenyl)-6-(pyrrolidin-1-yl)pyridazine-3-carboxamide (CAS 1396790-87-6)
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- 2-[(4-Chlorophenyl)amino]-4-(3-fluoro-4-methoxyphenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS 1349086-32-3)
- 2-Chloro-N-(3-cyano-4-(methylsulfonyl)phenyl)-4,5-difluorobenzamide (CAS 320421-61-2)
- 2-(4-Aminophenyl)-6-chloroquinoline-4-carboxylic acid (CAS 590357-66-7)
- 2,6-D (CAS 575-90-6)
- (4-Bromophenyl)(3-chlorophenyl)methanol (CAS 1226317-15-2)
- Ethyl 3-(2-chloro-8-methyl-4-oxo-quinazolin-3-yl)propanoate (CAS 2118563-46-3)
- 2-(3-Chloro-2-fluorophenyl)cyclopropanecarboxylic acid (CAS 1593692-08-0)
- 2-Fluoro-4-nitroaniline (CAS 369-35-7)
- N-benzyl-1-(4-(benzyloxy)phenyl)methanamine (CAS 69875-83-8)
- Phenylmethyl N-(2-aminoethyl)-N-methylcarbamate (CAS 19023-94-0)
- (2R,3R,4R,5R,6R)-6-(acetoxymethyl)-3-(pent-4-ynamido)tetrahydro-2H-pyran-2,4,5-triyl triacetate (CAS 1658458-26-4)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
Why CATO?
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