(Hydroxy(pyridin-4-yl)methyl)diphenylphosphine oxide CAS 260446-47-7

Purity 97%+In StockPharmaceutical Standards
CAS No.260446-47-7
Molecular FormulaC18H16NO2P
Molecular Weight309.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(Hydroxy(pyridin-4-yl)methyl)diphenylphosphine oxide CAS 260446-47-7 chemical structure

Description

(Hydroxy(pyridin-4-yl)methyl)diphenylphosphine oxide (CAS 260446-47-7), molecular formula C18H16NO2P and molecular weight 309.30 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, (Hydroxy(pyridin-4-yl)methyl)diphenylphosphine oxide (C18H16NO2P) contains a steroid core, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.5, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 309.30 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H16NO2P
Molecular Weight309.30 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1

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