2,6-Difluoro-3-nitrobenzoyl chloride CAS 260552-98-5
| CAS No. | 260552-98-5 |
| Molecular Formula | C7H2ClF2NO3 |
| Molecular Weight | 221.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2,6-Difluoro-3-nitrobenzoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2,6-Difluoro-3-nitrobenzoyl chloride (CAS 260552-98-5) is a high-purity analytical reference standard with the molecular formula C7H2ClF2NO3 and a molecular weight of 221.55 g/mol.
Structurally, 2,6-Difluoro-3-nitrobenzoyl chloride (C7H2ClF2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 221.55 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H2ClF2NO3 |
| Molecular Weight | 221.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,5-Difluoro-4-nitrobenzoyl chloride (CAS 1214385-18-8)
- 4,5-Difluoro-2-nitrobenzoyl chloride (CAS 129951-46-8)
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- 2,6-Difluoro-4-nitrobenzoyl chloride (CAS 1803730-46-2)
- 3,4-Difluoro-5-nitrobenzoyl chloride (CAS 1806313-22-3)
- 2,4-Difluoro-5-nitro-benzoylchloride (CAS 221560-09-4)
- 4,4-Difluoro-1-phenylcyclohexanecarbonitrile (CAS 1246744-42-2)
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Recommended Standards
- 5-Chloro-2-(trifluoromethoxy)benzonitrile (CAS 1092461-25-0)
- 2-Chloro-5-(trifluoromethyl)benzoxazole (CAS 114997-91-0)
- 2-Chloro-6-(trifluoromethyl)benzo[d]oxazole (CAS 1248393-79-4)
- 2-Chloro-5-(trifluoromethoxy)benzonitrile (CAS 1261644-07-8)
- tert-butyl (1S,4R)-2-oxo-7-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 163513-99-3)
- N-(5-Fluoresceinyl)-L-carnitine-O-thiocarbamate (CAS 1258239-73-4)
- (3ar,4as,7s,7as,8r,9ar)-4a,8-dimethyl-3-methylidene-2,5-dioxododecahydroazuleno[6,5-b]furan-7-yl 6-o-acetyl-|A-d-glucopyranoside 32314-39-9 KST-1A3794 (CAS 32314-39-9)
- 4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzaldehyde (CAS 1311278-58-6)
- Bromal (CAS 115-17-3)
- 7-bromo-3-methylthieno[3,2-c]pyridin-4-amine (CAS 2306263-16-9)
- 2-(3-((2,6-Difluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246827-16-5)
- N-(3-chloro-4-fluorophenyl)tetrahydro-2H-thiopyran-3-amine (CAS 1342164-47-9)
- Atogepant Impurity 74 (CAS CATO-C4X-328574)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com