6-Iodo-4,8-dimethylquinoline CAS 261636-07-1
| CAS No. | 261636-07-1 |
| Molecular Formula | C11H10IN |
| Molecular Weight | 283.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 283.11 g/mol gives 6-Iodo-4,8-dimethylquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Iodo-4,8-dimethylquinoline (CAS 261636-07-1) is a high-purity analytical reference standard with the molecular formula C11H10IN and a molecular weight of 283.11 g/mol.
6-Iodo-4,8-dimethylquinoline (C11H10IN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Iodo-4,8-dimethylquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10IN |
| Molecular Weight | 283.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 6-Iodo-2,7-dimethylquinoline (CAS 1934803-83-4)
- 5-Iodo-2,8-dimethylquinoline (CAS 1935281-62-1)
- 6-Iodo-2,5-dimethylquinoline (CAS 1936338-46-3)
- 3-iodo-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 862729-12-2)
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- 593255-20-0 2-Iodo-1,5-dimethyl-3-nitrobenzene DTXSID20556039 (CAS 593255-20-0)
- 4-Iodo-2-(methylsulfonyl)pyridine (CAS 1193244-95-9)
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Recommended Standards
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- 5-Chloro-2-(3-chlorophenoxy)benzoic acid (CAS 69199-64-0)
- Benzyl 2,4-dichloropyrimidine-5-carboxylate (CAS 69298-25-5)
- 5-Bromo-1-fluoro-2-methoxy-3-(methylsulfonyl)benzene (CAS 2411493-34-8)
- Methyl 2-oxo-2-(1H-pyrrol-2-yl)acetate (CAS 54224-26-9)
- trans-Tert-butyl-3,5-dimethylpiperazine-1-carboxylate (CAS 2216747-02-1)
- 7,8-Difluoroquinolin-3-amine (CAS 318685-32-4)
- 1-(5-Bromo-2-fluorophenyl)cyclopropanamine (CAS 1248503-74-3)
- 5-Chloro-1,4-dihydropyrimido[5,4-e][1,2,4]triazine (CAS 91115-01-4)
- 5-[3-amino-5-(trifluoromethyl)phenyl]-2,3-dihydro-1h-1,2,4-triazol-3-one (CAS 1244030-97-4)
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