N-(Piperidin-4-ylmethyl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide hydrochloride CAS 261767-16-2
| CAS No. | 261767-16-2 |
| Molecular Formula | C15H20N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(Piperidin-4-ylmethyl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-(Piperidin-4-ylmethyl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide hydrochloride (CAS 261767-16-2), a certified reference material (molecular formula C15H20N2O3HCl, MW 312.79 g/mol) for analytical method development and quality control.
N-(Piperidin-4-ylmethyl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide hydrochloride (C15H20N2O3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(Piperidin-4-ylmethyl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20N2O3 HCl |
| Molecular Weight | 312.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1000339-76-3 Ethyl 2-(Piperidin-1-yl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ethyl 2-(piperidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate ethyl 2-piperidin-1-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 1000339-76-3)
- 2-(Piperidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1000339-77-4)
- Benzyl 2-(piperidin-4-yl)acetate hydrochloride (CAS 1000872-47-8)
- n-(Piperidin-3-ylmethyl)morpholine-4-carboxamide (CAS 1000941-33-2)
- 1000958-55-3 4-Ethyl-1-[2-(piperidin-4-yl)ethyl]piperidine DTXSID60649257 (CAS 1000958-55-3)
- 5-(Piperidin-2-yl)pyridin-2-amine (CAS 100133-12-8)
- 5-(Piperidin-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione (CAS 100133-53-7)
- 1-methyl-5-(piperidin-1-ylcarbonyl)-1H-pyrazol-4-amine (CAS 1001500-82-8)
Recommended Standards
- Bivalirudin Impurity 1 (CAS 72378-50-8)
- N-(2-(1H-indol-3-yl)ethyl)acrylamide (CAS 25681-32-7)
- 4-Boronophenylthiocarboxamide (CAS 850589-35-4)
- 3-chloro-1H-indole-4-carboxylic acid (CAS 1556154-44-9)
- Nortracheloside (CAS 33464-78-7)
- 4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-1,3-thiazol-2-amine hydrochloride (CAS 1156039-78-9)
- N-[3-(Dimethylamino)Propyl]-1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-Sulphonamide (CAS 68555-77-1)
- 2-(4-(Difluoromethyl)-2,6-diiodopyridin-3-yl)acetic acid (CAS 1806799-16-5)
- 4,4-Dimethyl-1-(3-methylphenyl)-1,4-dihydropyrimidine-2-thiol (CAS 1142212-50-7)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
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