1-(2-Methyl-1H-indol-3-yl)-3-phenylprop-2-en-1-one CAS 26211-98-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Methyl-1H-indol-3-yl)-3-phenylprop-2-en-1-one.

1-(2-Methyl-1H-indol-3-yl)-3-phenylprop-2-en-1-one (CAS 26211-98-3), molecular formula C18H15NO and molecular weight 261.32 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 1-(2-Methyl-1H-indol-3-yl)-3-phenylprop-2-en-1-one is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 261.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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