5-(Trifluoromethyl)isobenzofuran-1,3-dione CAS 26238-14-2
| CAS No. | 26238-14-2 |
| Molecular Formula | C9H3F3O3 |
| Molecular Weight | 216.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 216.11 g/mol gives 5-(Trifluoromethyl)isobenzofuran-1,3-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-(Trifluoromethyl)isobenzofuran-1,3-dione (CAS 26238-14-2), a certified reference material (molecular formula C9H3F3O3, MW 216.11 g/mol) for analytical method development and quality control.
Structurally, 5-(Trifluoromethyl)isobenzofuran-1,3-dione (C9H3F3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 216.11 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(Trifluoromethyl)isobenzofuran-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H3F3O3 |
| Molecular Weight | 216.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)-4H-pyrido[3,4-d][1,3]oxazin-4-one (CAS 1437385-13-1)
- 2-(Trifluoromethyl)-4,7-dihydro-1H-1,3-benzodiazole-4,7-dione (CAS 478050-30-5)
- 6-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2,3-dione (CAS 2167294-81-5)
- 2,5-Bis-(Trifluoromethyl)pyrazine (CAS 1365988-35-7)
- 3,6-Bis(trifluoromethyl)-pyridazine (CAS 67096-93-9)
- 3-Oxo-3-(2-(trifluoromethyl)phenyl)propanal (CAS 1019029-43-6)
- 1-(4-(Trifluoromethyl)phenyl)propane-1,2-dione (CAS 10557-13-8)
- 1-(3-(Trifluoromethyl)phenyl)propane-1,2-dione (CAS 10557-15-0)
Recommended Standards
- 3-[(2,6-Dichlorophenyl)methyl]azetidine (CAS 937621-77-7)
- 5,6-Dichloro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 886762-72-7)
- 3,5-Dichloro-N-(cyclopropylmethyl)aniline (CAS 356539-48-5)
- 6,7-Dichloro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 59376-83-9)
- 6,7-Dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine (CAS 1899-39-4)
- 3-Methylhexanimidamide (CAS 1247201-65-5)
- Methyl 2-(1-Boc-4-piperidylidene)-2-(Cbz-amino)acetate (CAS 313491-20-2)
- 2-((Fluoro(phenyl)methyl)sulfonyl)pyridine (CAS 1689584-09-5)
- Lusutrombopag Impurity 23 (CAS CATO-C4X-208423)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-hydroxypyridine-5-acetonitrile (CAS 1807004-82-5)
- Diphenyl Methylphosphonate (CAS 7526-26-3)
- 4-Cyanobenzohydrazide (CAS 43038-36-4)
- 3,5-Dichloro-4-isopropoxybenzylamine hydrochloride (CAS 1052415-02-7)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com