N-Hydroxy-4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]benzenecarboximidamide CAS 263161-34-8
| CAS No. | 263161-34-8 |
| Molecular Formula | C13H10F3N3O2 |
| Molecular Weight | 297.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Hydroxy-4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]benzenecarboximidamide.
CATO supplies N-Hydroxy-4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]benzenecarboximidamide (CAS 263161-34-8), a certified reference material (molecular formula C13H10F3N3O2, MW 297.23 g/mol) for analytical method development and quality control.
Structurally, N-Hydroxy-4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]benzenecarboximidamide (C13H10F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 297.23 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10F3N3O2 |
| Molecular Weight | 297.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-Hydroxy-4-(2-(trifluoromethyl)phenoxy)picolinimidamide (CAS 1219454-16-6)
- N-Hydroxy-4-(3-(trifluoromethoxy)phenyl)picolinimidamide (CAS 1219454-23-5)
- 2-hydroxy-N-[4-(trifluoromethoxy)phenyl]benzamide (CAS 224814-88-4)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(pyrrolidin-1-yl)thiophen-2-yl)boronate (CAS 2223039-68-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(pyrrolidin-1-yl)thiophen-2-yl)boronate (CAS 2223049-91-8)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(pyrrolidin-1-yl)thiophen-3-yl)boronate (CAS 2223045-40-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-cyclopentylthiazol-4-yl)boronate (CAS 2223033-19-8)
- 7-Hydroxy-2-methyl-3-(4-nitrophenyl)-4h-chromen-4-one (CAS 314243-90-8)
Recommended Standards
- N-(4-bromobenzyl)-1-ethylpiperidin-4-amine (CAS 415954-96-0)
- Se-Phenyl benzenesulfonoselenoate (CAS 60805-71-2)
- N-(3-bromobenzyl)-1-ethylpiperidin-4-amine (CAS 415960-24-6)
- 3-(3,5-Bis(trifluoromethyl)phenyl)piperidine (CAS 1187228-26-7)
- 2-Chloro-N-((2-(4-chlorophenyl)-4-methylthiazol-5-yl)methyl)benzenesulfonamide (CAS 866018-51-1)
- 1-Bromo-4-methoxy-2-(phenoxymethyl)benzene (CAS 866097-01-0)
- Methyl5-methoxy-1h-pyrrolo[2,3-c]pyridine-3-carboxylate (CAS 2118403-09-9)
- 1-(5-bromo-1H-indol-3-yl)-2-chloro-ethanone (CAS 65040-36-0)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)-2-methylpropanoic acid (CAS 914399-98-7)
- Z-Asp(OBzl)-OH (CAS 3479-47-8)
- Ethyl 5-bromo-2-((2-methoxyethyl)amino)pyrimidine-4-carboxylate (CAS 1316122-39-0)
- [(4-Bromophenyl)methyl](cyclopropylmethyl)amine (CAS 1019538-77-2)
- 1-(2-(Methylsulfonyl)ethyl)cyclobutan-1-amine (CAS 1538879-52-5)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
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