Thalidomide-5'-piperidine CAS 2636798-56-4
| CAS No. | 2636798-56-4 |
| Molecular Formula | C18H20N4O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 392.84 g/mol gives Thalidomide-5'-piperidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Thalidomide-5'-piperidine (CAS 2636798-56-4), molecular formula C18H20N4O4HCl and molecular weight 392.84 g/mol, is a CATO reference standard with documented purity and traceability.
Thalidomide-5'-piperidine (C18H20N4O4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Thalidomide-5'-piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O4 2*HCl |
| Molecular Weight | 392.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Thalidomide Standards
- Thalidomide-propargyl-OH (CAS 1216805-67-2)
- Thalidomide-d4 (CAS 1219177-18-0)
- Thalidomide Impurity 3 (CAS 126663-38-5)
- Thalidomide-5,6-F (CAS 1496997-41-1)
- Thalidomide-O-amido-C4-NH2 (CAS 1799711-24-2)
- Thalidomide-O-amido-C3-PEG3-C1-NH2 (CAS 1799711-29-7)
- Thalidomide-O-amido-C6-NH2 (CAS 1950635-13-8)
- Thalidomide-O-amido-C6-NH2 (TFA) (CAS 1950635-14-9)
Recommended Standards
- N-(2,5-Dimethoxyphenyl)-2-((4-phenyl-5-((p-tolylamino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332907-12-7)
- 2-(Benzylamino)-1-(4-fluorophenyl)ethan-1-ol (CAS 920796-72-1)
- 1-Iodohex-3-yne (CAS 102998-71-0)
- Methyl 3,5-difluoro-2-hydroxybenzoate (CAS 180068-67-1)
- Ethyl 5-(2,2,2-trifluoroethyl)-1,2,4-oxadiazole-3-carboxylate (CAS 1340420-88-3)
- 4-Hexylphenyl 4-(trans-4-heptylcyclohexyl)benzoate (CAS 84601-00-3)
- Methyl 2-((5-(3-phenylureido)-1,3,4-thiadiazol-2-yl)thio)propanoate (CAS 898437-14-4)
- Ethyl[(2-fluorophenyl)methyl]amine (CAS 64567-25-5)
- 2-(2-(4-Fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443344-67-9)
- Tau Peptide (379-408) trifluoroacetate salt (CAS 1246357-53-8)
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