Methyl 5-(dimethylphosphoryl)thiophene-2-carboxylate CAS 2639427-93-1

Purity 97%+In StockPharmaceutical Standards
CAS No.2639427-93-1
Molecular FormulaC8H11O3PS
Molecular Weight218.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 5-(dimethylphosphoryl)thiophene-2-carboxylate CAS 2639427-93-1 chemical structure

Description

The occurrence of Methyl 5-(dimethylphosphoryl)thiophene-2-carboxylate is closely related to a sulfone group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Methyl 5-(dimethylphosphoryl)thiophene-2-carboxylate (CAS 2639427-93-1), a certified reference material (molecular formula C8H11O3PS, MW 218.21 g/mol) for analytical method development and quality control.

The molecular framework of Methyl 5-(dimethylphosphoryl)thiophene-2-carboxylate (C8H11O3PS) is characterized by a sulfone group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H11O3PS
Molecular Weight218.21 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2001
Sulfur Atoms1

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