3-(Benzyloxy)-4-hydroxy-5-iodobenzaldehyde CAS 264278-45-7
| CAS No. | 264278-45-7 |
| Molecular Formula | C14H11IO3 |
| Molecular Weight | 354.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(Benzyloxy)-4-hydroxy-5-iodobenzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-(Benzyloxy)-4-hydroxy-5-iodobenzaldehyde (CAS 264278-45-7), a certified reference material (molecular formula C14H11IO3, MW 354.14 g/mol) for analytical method development and quality control.
The molecular framework of 3-(Benzyloxy)-4-hydroxy-5-iodobenzaldehyde (C14H11IO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H11IO3 |
| Molecular Weight | 354.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
Related Benzyloxy Standards
- 3-(Benzyloxy)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (CAS 2377610-61-0)
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid (CAS 98409-91-7)
- 3-(3-(4-(Benzyloxy)-3-methoxyphenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 889946-66-1)
- 2-(4-(Benzyloxy)butyl)-4,6-dimethoxy-3-methylbenzofuran (CAS 831171-02-9)
- Methyl 2-{[(benzyloxy)carbonyl]amino}-3-(4,5-dihydro-1,3-thiazol-2-ylsulfanyl)propanoate (CAS 691880-97-4)
- (S)-4-(benzyloxy)-2-((1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (CAS 2206743-00-0)
- 1-(3-(Benzyloxy)pyridin-2-yl)-3-(3-chlorophenyl)urea (CAS 877459-37-5)
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Recommended Standards
- 3-(4-Iodophenoxymethyl)benzoic acid (CAS 693237-06-8)
- 3-Iodo-N-(6-methoxypyridin-3-yl)benzamide (CAS 853703-70-5)
- 2,5-Dibromo-3,4-dibutylthiophene (CAS 247088-06-8)
- 4-((4-Iodophenoxy)methyl)benzoic acid (CAS 438531-38-5)
- 2-(3,4-Dihydroxyphenyl)ethyl-1,1-d2-amine HCl (CAS 83008-33-7)
- 2-Methyl-4-(trifluoromethyl)imidazole (CAS 33468-67-6)
- [Dideuterio-(2,3,3-trideuteriooxiran-2-yl)methyl] tetradecanoate (CAS 1330180-72-7)
- 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1-ol (CAS 2248157-58-4)
- 13-cis-Retinoic Acid Ethyl Ester (CAS 59699-82-0)
- N-Acetyl-2-O-methyl-α-neuraminic Acid 9-Acetate (CAS 143791-32-6)
- 2-Bromo-N-(4-bromophenyl)propanamide (CAS 42276-46-0)
- 1,2-Dimethyl-5,6-dihydro-1H-indol-7(4H)-one (CAS 182883-80-3)
- Methyl 2-amino-5-(3-fluorophenyl)-1,3-thiazole-4-carboxylate (CAS 127918-93-8)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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