3-(difluoromethyl)-N',N',1-trimethyl-pyrazole-4-carbohydrazide CAS 2648106-02-7
| CAS No. | 2648106-02-7 |
| Molecular Formula | C8H16F2N4O |
| Molecular Weight | 222.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(difluoromethyl)-N',N',1-trimethyl-pyrazole-4-carbohydrazide (C8H16F2N4O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3-(difluoromethyl)-N',N',1-trimethyl-pyrazole-4-carbohydrazide (CAS 2648106-02-7) is a high-purity analytical reference standard with the molecular formula C8H16F2N4O and a molecular weight of 222.24 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(difluoromethyl)-N',N',1-trimethyl-pyrazole-4-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H16F2N4O |
| Molecular Weight | 222.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related difluoromethyl Standards
- (S)-3-(difluoromethyl)-2-(pyrrolidin-2-yl)benzonitrile (CAS 1446982-17-7)
- 2-(Difluoromethyl)-3-methylpyridine-5-sulfonamide (CAS 1805010-76-7)
- 4-(Difluoromethyl)-5-methylpyridine-2-sulfonamide (CAS 1805122-65-9)
- 2-(Difluoromethyl)-4-methylpyridine-3-sulfonamide (CAS 1805320-99-3)
- 7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1160246-22-9)
- 2-(Difluoromethyl)naphthalene-7-carboxylic acid (CAS 1261489-05-7)
- 7-(Difluoromethyl)-1-naphthoic acid (CAS 1261588-48-0)
- 1-(Difluoromethyl)naphthalene-6-carboxylic acid (CAS 1261600-10-5)
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- 1-(2,6-Dichloro-3,5-dimethoxyphenyl)piperidin-4-one (CAS 2168560-14-1)
- 5,7-Dibromo-2,3-dihydrothieno[3,4-β][1,4]dioxine (CAS 174508-31-7)
- (Dimethylsulfamoyl)methylamine (CAS 76820-42-3)
- Ethyl (3-methylbenzyl)glycinate (CAS 501653-59-4)
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- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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