(4-Fluoro-2-methoxy-3-methylphenyl)boronic acid CAS 2649471-84-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2649471-84-9
Molecular FormulaC8H10BFO3
Molecular Weight183.97 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(4-Fluoro-2-methoxy-3-methylphenyl)boronic acid CAS 2649471-84-9 chemical structure

Description

The occurrence of (4-Fluoro-2-methoxy-3-methylphenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(4-Fluoro-2-methoxy-3-methylphenyl)boronic acid (CAS 2649471-84-9) is a high-purity analytical reference standard with the molecular formula C8H10BFO3 and a molecular weight of 183.97 g/mol.

The molecular framework of (4-Fluoro-2-methoxy-3-methylphenyl)boronic acid (C8H10BFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (4-Fluoro-2-methoxy-3-methylphenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H10BFO3
Molecular Weight183.97 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2002
Halogen ContentF-containing

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