2-Fluoro-3-iodo-6-methyl-5-nitrobenzoic acid CAS 2654793-75-4
| CAS No. | 2654793-75-4 |
| Molecular Formula | C8H5FINO4 |
| Molecular Weight | 325.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Fluoro-3-iodo-6-methyl-5-nitrobenzoic acid (CAS 2654793-75-4), molecular formula C8H5FINO4 and molecular weight 325.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Fluoro-3-iodo-6-methyl-5-nitrobenzoic acid (C8H5FINO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H5FINO4 |
| Molecular Weight | 325.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- Methyl 2-fluoro-4-iodo-5-nitrobenzoate (CAS 1807741-24-7)
- 2-Fluoro-4,6-bis(trifluoromethyl)benzyl bromide (CAS 1017778-46-9)
- 3-Fluoro-4-(pentafluoroethylthio)bromobenzene (CAS 1301739-36-5)
- (4-(N-(4-Fluoro-3-methoxyphenyl)sulfamoyl)phenyl)boronic acid (CAS 957120-99-9)
- n-(4-Fluoro-2-iodophenyl)-2-(methylthio)acetamide (CAS 1394744-29-6)
- 2-Fluoro-4-(5-hydroxy-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide (CAS 358742-72-0)
- 3-Fluoro-4-(((2-(2,2,2-trifluoroethoxy)pyridin-4-yl)methyl)amino)benzonitrile (CAS 1280882-25-8)
- 5-Fluoro-2-(4-fluorobenzoyl)benzoic acid (CAS 250714-85-3)
Recommended Standards
- 3,5-Dibromo-1-heptyl-1H-1,2,4-triazole (CAS 1240572-20-6)
- 2-Bromo-n-(2,5-dichlorophenyl)-3-methylbutanamide (CAS 1017029-14-9)
- 4,6-Dibromo-2-mercaptobenzothiazole (CAS 1309379-11-0)
- n-Allyl-4,5-dibromothiophene-2-carboxamide (CAS 950150-38-6)
- N-Cyclohexyl-2-bromo-5-fluorobenzamide (CAS 951884-99-4)
- 3-Acetamido-5-bromobenzoic acid (CAS 78238-11-6)
- 2-(Aminomethyl)-3-cyano-5-(difluoromethyl)-4-methylpyridine (CAS 1806982-40-0)
- 4-Ethynyl-2-fluoro-1-methoxybenzene (CAS 120136-28-9)
- 1,1'-(2,3-Dihydroquinoxaline-1,4-diyl)bis(4-chlorobutan-1-one) (CAS 6699-43-0)
- Ibuprofen Impurity 156 (CAS CATO-C4X-1082156)
- 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanol (sodium salt) 1,2-dioleoyl-sn-glycero-3-phosphoethanol (sodium salt) 18:1 Phosphatidylethanol 322647-53-0 (CAS 322647-53-0)
- 2,4,5-Trimethyl-1-(pyridin-2-yl)-1H-pyrrole-3-carbaldehyde (CAS 1087611-23-1)
- 4-[Bis(4-methoxyphenyl)amino]benzaldehyde (CAS 89115-20-8)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com