TEtrakis(1,1,1,3,3,3-hexafluoroisopropoxy)silane CAS 26560-90-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including TEtrakis(1,1,1,3,3,3-hexafluoroisopropoxy)silane.

TEtrakis(1,1,1,3,3,3-hexafluoroisopropoxy)silane (CAS 26560-90-7) is a high-purity analytical reference standard with the molecular formula C12H4F24O4Si and a molecular weight of 696.20 g/mol.

The molecular framework of TEtrakis(1,1,1,3,3,3-hexafluoroisopropoxy)silane (C12H4F24O4Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), TEtrakis(1,1,1,3,3,3-hexafluoroisopropoxy)silane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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