para-Hydroxy Atorvastatin-d5 Calcium Salt CAS 265989-45-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.265989-45-5
Molecular Formula-
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

para-Hydroxy Atorvastatin-d5 Calcium Salt CAS 265989-45-5 chemical structure

Description

The occurrence of para-Hydroxy Atorvastatin-d5 Calcium Salt is closely related to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies para-Hydroxy Atorvastatin-d5 Calcium Salt (CAS 265989-45-5), a pharmacopoeial impurity reference standard (molecular formula C33H29D5FN2O6Ca, MW 618.75 g/mol) used for the identification and quantification of trace impurities in APIs.

para-Hydroxy Atorvastatin-d5 Calcium Salt (C33H29D5FN2O6Ca) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular Formula2*C33H29D5FN2O6 Ca
Molecular Weight618.75 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)20.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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