4,4'-Thiobis-phenol CAS 2664-63-3
| CAS No. | 2664-63-3 |
| Molecular Formula | C12H10O2S |
| Molecular Weight | 218.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 218.27 g/mol gives 4,4'-Thiobis-phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4,4'-Thiobis-phenol (CAS 2664-63-3) is a high-purity analytical reference standard with the molecular formula C12H10O2S and a molecular weight of 218.27 g/mol.
The molecular framework of 4,4'-Thiobis-phenol (C12H10O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,4'-Thiobis-phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10O2S |
| Molecular Weight | 218.27 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Sulfur Atoms | 1 |
Related Thiobis Standards
- 6,6'-Thiobis(pyridin-3-amine) (CAS 32605-02-0)
- 4,4'-Thiobis(2-methylphenol) (CAS 24197-34-0)
- 1,1'-(Thiobis(4,1-phenylene))diethanone (CAS 2615-09-0)
- 2,2'-Thiobis(1-phenylethan-1-one) (CAS 2461-80-5)
- Thiobis(ethane-2,1-diyl) bis(3-aminobut-2-enoate) (CAS 13560-49-1)
- 3,3'-Thiobis(3-phenylpropan-1-ol) (CAS 26524-88-9)
- 1,1'-Thiobis(naphthalen-2-ol) (CAS 17096-15-0)
- 2,2'-Thiobis(isoindoline-1,3-dione) (CAS 7764-29-6)
Recommended Standards
- Diphenyl Sulfone (CAS 127-63-9)
- 1-Ethyl-3,5-dimethyl-1h-pyrazole-4-sulfonohydrazide (CAS 1006356-40-6)
- Sulfanilamide-d4 (CAS 77435-46-2)
- 7-Phenyl-6,7-dihydro-5h-imidazo[2,1-c][1,2,4]triazole-3-thiol (CAS 1105189-88-5)
- Ethyl 4-Acetamidophenylacetate (CAS 13475-17-7)
- 6-Acetyl-1h,2h,3h-thieno[2,3-b][1,4]thiazin-2-one (CAS 151095-12-4)
- (2-phenoxypyridin-4-yl)methanamine dihydrochloride (CAS 1989659-70-2)
- (2S)-2-[(4S,5R)-4,5-Dihydro-4,5-diphenyl-2-oxazolyl]-1-(diphenylphosphino)piperidine (CAS 2757084-49-2)
- 4-(Methylsulfonyl)benzene-1,2-diamine (CAS 21731-57-7)
- 7-Chloro-2-cyclobutyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1379811-78-5)
- Moxifloxacin Impurity 67 (CAS 151213-39-7 (free base))
- 2,6,14-Triiodo-9,10-dihydro-9,10-[1,2]benzenoanthracene (CAS 910324-13-9)
- 4,4',4''-(((1,3,5-Triazine-2,4,6-triyl)tris(benzene-4,1-diyl))tris(ethyne-2,1-diyl))trianiline (CAS 2803476-79-9)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com