2-(2,3-Difluoro-4-(fluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 2673219-39-9
| CAS No. | 2673219-39-9 |
| Molecular Formula | C13H16BF3O3 |
| Molecular Weight | 288.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-(2,3-Difluoro-4-(fluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2673219-39-9), a certified reference material (molecular formula C13H16BF3O3, MW 288.07 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2,3-Difluoro-4-(fluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C13H16BF3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-(2,3-Difluoro-4-(fluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16BF3O3 |
| Molecular Weight | 288.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
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Recommended Standards
- 2-(2-(Difluoromethoxy)-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2375423-84-8)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)phenol (CAS 2055742-98-6)
- 2-(2-(Difluoromethoxy)-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621936-65-8)
- 2-(4-Methoxy-2-(trifluoromethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane (CAS 2096997-63-4)
- 1,3,5-Triethyl-1,3,5-triazinane (CAS 7779-27-3)
- 1-(tert-Butoxycarbonyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1781907-25-2)
- 4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-N'-hydroxybenzenecarboximidamide (CAS 341967-76-8)
- 1-Amino-2-butanol (CAS 13552-21-1)
- 5-Bromo-2-fluoro-3-(trifluoroacetamido)phenylboronic acid (CAS 2377606-75-0)
- 2-(4-Methoxyphenyl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid (CAS 75810-50-3)
- 4-(2,4-Dioxocyclohexyl)benzonitrile (CAS 120630-23-1)
- 4-Cyclopropoxy-N-methyl-5-nitropicolinamide (CAS 1243348-47-1)
- (3,5-dimethylcyclohexyl)methanol (CAS 68480-16-0)
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