5-Chloro-1,2,3-trimethoxybenzene CAS 2675-80-1
| CAS No. | 2675-80-1 |
| Molecular Formula | C9H11ClO3 |
| Molecular Weight | 202.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-1,2,3-trimethoxybenzene.
5-Chloro-1,2,3-trimethoxybenzene (CAS 2675-80-1), molecular formula C9H11ClO3 and molecular weight 202.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-1,2,3-trimethoxybenzene (C9H11ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-1,2,3-trimethoxybenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11ClO3 |
| Molecular Weight | 202.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 1-Chloro-4-(cyclopropyldifluoromethyl)benzene (CAS 1204296-10-5)
- 2-Chloro-1,3-difluoro-5-(2-methylallyl)benzene (CAS 1256470-65-1)
- (4-Chloro-2,5-dimethoxyphenyl)methanol (CAS 1394837-77-4)
- 4-CHloro-3-(2-methoxyethoxy)phenol (CAS 1394968-35-4)
- 3-Chloro-5-(2-methoxyethoxy)phenol (CAS 1394974-97-0)
- 2-Chloro-1,3,4-trimethoxybenzene (CAS 140665-34-5)
- (3-Chloro-4,5-dimethoxyphenyl)methanol (CAS 18268-78-5)
- 2-Chloro-5-(2-methoxyethoxy)phenol (CAS 1881291-29-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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