3-Chlorophenylglyoxylic acid CAS 26767-07-7
| CAS No. | 26767-07-7 |
| Molecular Formula | C8H5ClO3 |
| Molecular Weight | 184.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chlorophenylglyoxylic acid (CAS 26767-07-7), molecular formula C8H5ClO3 and molecular weight 184.58 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 3-Chlorophenylglyoxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5ClO3 |
| Molecular Weight | 184.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
Recommended Standards
- 3-Chloro-6-methoxy-[1,2,4]triazolo[4,3-b]pyridazine (CAS 33048-27-0)
- 3-Formylphenyl chloroformate (CAS 70093-69-5)
- 3-Chloro-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine (CAS 917482-81-6)
- 4-Chloro-1H-indazole-3,6-diol (CAS 887570-67-4)
- 2-(3,4,5-trifluorophenyl)acetic acid 209991-62-8 3,4,5-trifluorophenylacetic acid A24090 (CAS 209991-62-8)
- tert-Butyl N-(4-aminophenyl)-N-methylcarbamate (CAS 1092522-02-5)
- Trans-4-((4-ethylisoquinolin-5-yl)oxy)cyclohexanamine (CAS 651308-52-0)
- 2-Chloro-4-(3-(trifluoromethyl)phenyl)-1,3,5-triazine (CAS 1053658-32-4)
- Naltrexone Impurity 11 (CAS 123086-68-0)
- N-(4-bromophenyl)-4-hydrazinyl-4-oxobutanamide (CAS 443863-36-3)
- 5-(4-Fluorophenyl)-3-methylpentanoic acid (CAS 1343599-89-2)
- Methyl 5-bromo-1H-indole-4-carboxylate (CAS 731810-04-1)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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