(E)-7-Iodo-3-(iodomethylene)-3,4-dihydro-1H-[1,4]oxazepino[6,5,4-hi]indol-1-one CAS 2677022-53-4
| CAS No. | 2677022-53-4 |
| Molecular Formula | C12H7I2NO2 |
| Molecular Weight | 451.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-7-Iodo-3-(iodomethylene)-3,4-dihydro-1H-[1,4]oxazepino[6,5,4-hi]indol-1-one.
CATO supplies (E)-7-Iodo-3-(iodomethylene)-3,4-dihydro-1H-[1,4]oxazepino[6,5,4-hi]indol-1-one (CAS 2677022-53-4), a certified reference material (molecular formula C12H7I2NO2, MW 451.00 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution, (E)-7-Iodo-3-(iodomethylene)-3,4-dihydro-1H-[1,4]oxazepino[6,5,4-hi]indol-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 451.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-7-Iodo-3-(iodomethylene)-3,4-dihydro-1H-[1,4]oxazepino[6,5,4-hi]indol-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7I2NO2 |
| Molecular Weight | 451.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- 2-((1-Acetyl-3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity) (CAS 1639138-00-3)
- 2-Iodo-2,4,6-triisopropyl-3-methoxy-6-methylbiphenyl (CAS 1351403-03-6)
- Ethyl 8-iodo-2,6-bis(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1171918-86-7)
- 2-Iodo-N-(3-(2-methoxyethyl)-6-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide (CAS 864975-06-4)
- 2-(2-Iodo-6-methoxyquinolin-3-yl)-5,7-dimethyl-1,3-diazaadamantane (CAS 1442540-55-7)
- 4-Iodo-N-(4-iodophenyl)benzamide (CAS 121724-15-0)
- 1-(5-Iodo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)-2,2-dimethylpropan-1-one (CAS 2390149-25-2)
- 2-Iodo-1h,1h,2h,3h,3h-perfluorooctan-1-ol (CAS 16083-66-2)
Recommended Standards
- N-(5-chloro-2-methoxyphenyl)-2-((N-cyclohexyl-4-methylphenyl)sulfonamido)acetamide (CAS 332163-17-4)
- H-D-Pro-Phe-Arg-chloromethylketone (CAS 88546-74-1)
- Methyl 2-(2-(4-chlorophenyl)acetamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 335408-88-3)
- Bis((1r,2s,5r)-2-isopropyl-5-methylcyclohexyl) ((r)-3-chloro-2-hydroxypropyl)phosphonate (CAS 945652-59-5)
- (R)-Naproxen Acyl-β-D-glucuronide (CAS 112828-15-6)
- 3-Nonyl-4-octyl-1H-pyrazol-5(4H)-one (CAS 91990-64-6)
- Dihydro-N-Caffeoyl Tyramine (CAS 501939-19-1)
- 4-(tert-Butyl)-2-cyclopropoxy-1-methoxybenzene (CAS 1243395-83-6)
- 4-Amino-3-bromo-6-fluoroindazole (CAS 885522-95-2)
- 3-((2,6-Dichlorobenzyl)sulfonyl)-N-(p-tolyl)thiophene-2-carboxamide (CAS 251097-78-6)
- N-(3-Bromo-1-methyl-1H-indazol-5-yl)acetamide (CAS 1788044-08-5)
- 2-(2-(Pyridin-3-yl)thiazol-5-yl)ethanamine (CAS 1267025-22-8)
- 3-Chloro-4-fluoro-N-(furan-3-ylmethyl)-N-(2-methoxyethyl)benzenesulfonamide (CAS 1421442-18-3)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com