tert-Butyl 8-bromo-6-chloro-3,4-dihydroisoquinoline-2(1H)-carboxylate CAS 2680889-40-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2680889-40-9
Molecular FormulaC14H17BrClNO2
Molecular Weight346.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 8-bromo-6-chloro-3,4-dihydroisoquinoline-2(1H)-carboxylate CAS 2680889-40-9 chemical structure

Description

The occurrence of tert-Butyl 8-bromo-6-chloro-3,4-dihydroisoquinoline-2(1H)-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies tert-Butyl 8-bromo-6-chloro-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 2680889-40-9), a certified reference material (molecular formula C14H17BrClNO2, MW 346.65 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, tert-Butyl 8-bromo-6-chloro-3,4-dihydroisoquinoline-2(1H)-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 346.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures tert-Butyl 8-bromo-6-chloro-3,4-dihydroisoquinoline-2(1H)-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H17BrClNO2
Molecular Weight346.65 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentCl/Br-containing
Nitrogen Atoms1

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