Ethyl 6,7-dichloro-4-hydroxyquinoline-3-carboxylate CAS 26892-93-3
| CAS No. | 26892-93-3 |
| Molecular Formula | C12H9Cl2NO3 |
| Molecular Weight | 286.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 6,7-dichloro-4-hydroxyquinoline-3-carboxylate (C12H9Cl2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ethyl 6,7-dichloro-4-hydroxyquinoline-3-carboxylate (CAS 26892-93-3) is a high-purity analytical reference standard with the molecular formula C12H9Cl2NO3 and a molecular weight of 286.11 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 6,7-dichloro-4-hydroxyquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9Cl2NO3 |
| Molecular Weight | 286.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2,5-Dichloro-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)benzamide (CAS 1207055-26-2)
- Ethyl 6,7-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 122224-58-2)
- 3,4-Dichloro-1-(2-ethoxyphenyl)-1H-pyrrole-2,5-dione (CAS 138509-79-2)
- Ethyl 4,6-Dichloro-3-formyl-2-indolecarboxylate (CAS 153435-96-2)
- Ethyl 5,7-dichloro-4-hydroxyquinoline-2-carboxylate (CAS 157848-08-3)
- Ethyl 7,8-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 175134-95-9)
- 2-[(5,7-dichloro-2-methylquinolin-8-yl)oxy]acetic acid (CAS 730950-02-4)
- 5,7-Dichloro-8-methoxyquinoline-3-carbohydrazide (CAS 648897-25-0)
Recommended Standards
- Ethyl 5-chloro-1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate (CAS 30165-93-6)
- Ethyl 6,8-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 25771-89-5)
- Ethyl 5,8-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 35975-58-7)
- Ethyl 7,8-dichloro-4-hydroxyquinoline-3-carboxylate (CAS 75001-53-5)
- N-Butyl-N-(3-nitrophenyl)methanesulfonamide (CAS 1820618-28-7)
- Ethyl 2-amino-3-fluorobenzoate (CAS 144851-84-3)
- Bis(4-fluorophenyl)methanamine (CAS 55095-27-7)
- 3-(5-(Trifluoromethyl)pyridin-3-yl)-1H-indazol-5-amine (CAS 1356088-08-8)
- (2,3-Difluorophenyl)(quinolin-3-yl)methanone (CAS 1187166-32-0)
- (3-methyltetrahydrofuran-2-yl)methanol (CAS 89534-33-8)
- N-methyl-2-phenylcyclopropan-1-amine hydrochloride (CAS 90874-45-6)
- Ethyl 2-(Aminomethyl)pentanoate Hydrochloride (CAS 1803566-51-9)
- 2-(Difluoromethyl)-5-methyl-3-nitropyridine-4-carbonyl chloride (CAS 1806886-58-7)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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