Fmoc-R-3-amino-4-(3-trifluoromethylphenyl)-butyric acid CAS 269726-75-2
| CAS No. | 269726-75-2 |
| Molecular Formula | C26H22F3NO4 |
| Molecular Weight | 469.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Fmoc-R-3-amino-4-(3-trifluoromethylphenyl)-butyric acid (CAS 269726-75-2), a certified reference material (molecular formula C26H22F3NO4, MW 469.45 g/mol) for analytical method development and quality control.
The molecular framework of Fmoc-R-3-amino-4-(3-trifluoromethylphenyl)-butyric acid (C26H22F3NO4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Fmoc-R-3-amino-4-(3-trifluoromethylphenyl)-butyric acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H22F3NO4 |
| Molecular Weight | 469.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- Fmoc-4-trifluoromethyl-L-homophenylalanine (CAS 1260591-49-8)
- Fmoc-3-trifluoromethyl-L-homophenylalanine (CAS 1260593-06-3)
- Fmoc-(S)-3-Amino-4-(4-Trifluoromethyl-phenyl)-butyric acid (CAS 270065-81-1)
- Fmoc-N-Me-(4-CF3)-Phe-OH (CAS 2255321-51-6)
- N-Fmoc-L-Phe(4-cyclohexyl)-OH (CAS 1381801-21-3)
- Fmoc-3,4-dichloro-L-homophenylalanine (CAS 1260616-12-3)
- Fmoc-3,4-dichloro -D-homophenylalanine (CAS 1260618-71-0)
- (S)-3-(Fmoc-amino)-4-(2,4-dichlorophenyl)butanoic Acid (CAS 270063-49-5)
Recommended Standards
- (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[4-(trifluoromethyl)phenyl]butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[4-(trifluoromethyl)phenyl]butyric acid (3R)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-[4-(trifluoromethyl)phenyl]butanoic acid 269726-78-5 Fmoc-(R)-3-Amino-4-(4-trifluoromethylphenyl)-butyric acid (CAS 269726-78-5)
- Cefixime Impurity 12 (CAS 1335555-87-7)
- 4-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-6-[(4-chlorophenyl)sulfanyl]-2-phenylpyrimidine (CAS 338960-93-3)
- Cefixime Impurity 55 (CAS CATO-C4X-113955)
- 4-(Chloromethyl)-2-(2-methoxyphenyl)thiazole (CAS 129486-80-2)
- 4-(Chloromethyl)-2-fluoro-3-methylpyridine (CAS 1227594-61-7)
- 4-(6-(4-Hydroxypiperidin-1-yl)-3-methylpicolinamido)-3,5-dimethylbenzoic acid (CAS 1529760-74-4)
- Dabigatran Impurity 113 (CAS CATO-C4X-1089113)
- 2-((1R,4r)-4-(4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)phenyl)cyclohexyl)acetic acid (CAS 1031336-63-6)
- (3-Fluoro-5-(2,2,2-trifluoroethoxy)phenyl)boronic acid (CAS 850589-55-8)
- N-(3-acetylphenyl)-5-bromofuran-2-carboxamide (CAS 312704-44-2)
- S-((5-(Pyridin-3-yl)furan-2-yl)methyl) ethanethioate (CAS 859239-18-2)
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Why CATO?
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