(R)-2-Amino-2-(3-chloro-5-fluorophenyl)ethan-1-ol hydrochloride CAS 2703745-58-6

Description

Compared with other compounds in its class, the molecular weight of 226.07 g/mol gives (R)-2-Amino-2-(3-chloro-5-fluorophenyl)ethan-1-ol hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(R)-2-Amino-2-(3-chloro-5-fluorophenyl)ethan-1-ol hydrochloride (CAS 2703745-58-6), molecular formula C8H9ClFNOHCl and molecular weight 226.07 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (R)-2-Amino-2-(3-chloro-5-fluorophenyl)ethan-1-ol hydrochloride (C8H9ClFNOHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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