Salicylic acid impurity 30 CAS 2704-58-7
| CAS No. | 2704-58-7 |
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Salicylic acid impurity 30 (CAS 2704-58-7, C12H14O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Salicylic acid impurity 30 (C12H14O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Salicylic acid impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Salicylic Standards
- Salicylic Acid Impurity 17 (CAS 870806-51-2)
- Salicylic Acid Benzyl Ester (CAS 118-58-1)
- Salicylic Acid Impurity 19 (CAS CATO-C4X-190219)
- Salicylic Acid Impurity 35 (CAS CATO-C4X-190235)
- Salicylic acid-pentyl ester (CAS 2050-08-0)
- Salicylic Acid Impurity 26 (CAS 83957-15-7)
- Salicylic Acid Impurity 21 (CAS CATO-C4X-190221)
- Salicylic acid Impurity 28 (CAS 32499-37-9)
Recommended Standards
- Esmolol Impurity 39 (CAS 54965-55-8)
- Tetracaine Impurity 41 (CAS CATO-C4X-192341)
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- Lornoxicam Impurity 42 (CAS CATO-C4X-201642)
- Prednisolone Impurity 53 (CAS CATO-C4X-173753)
- Iopamidol Impurity 35 (CAS CATO-C4X-145035)
- Sodium Valproate Impurity 19 (CAS 616-62-6)
- [4'-(Methylsulfonyl)[1,1'-biphenyl]-4-yl] acetonitrile (CAS 893737-90-1)
- N-(2-((4-chlorophenyl)thio)ethyl)-6,7-dimethoxyquinazolin-4-amine (CAS 477859-98-6)
- Ethyl 6,6-dimethylhept-2-en-4-ynoate (CAS 60739-66-4)
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- (E)-N-Phenyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanimine (CAS 1073372-06-1)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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