2-[(3-methylphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one CAS 27052-16-0

Purity 97%+In StockPharmaceutical Standards
CAS No.27052-16-0
Molecular FormulaC10H10N2OS
Molecular Weight206.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[(3-methylphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one CAS 27052-16-0 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

CATO supplies 2-[(3-methylphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one (CAS 27052-16-0), a certified reference material (molecular formula C10H10N2OS, MW 206.26 g/mol) for analytical method development and quality control.

The molecular framework of 2-[(3-methylphenyl)amino]-4,5-dihydro-1,3-thiazol-4-one (C10H10N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC10H10N2OS
Molecular Weight206.26 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1964
Nitrogen Atoms2
Sulfur Atoms1

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