(R)-1-(3-aminopyrrolidin-1-yl)-2,2,2-trifluoroethan-1-one CAS 270584-80-0

Description

(R)-1-(3-aminopyrrolidin-1-yl)-2,2,2-trifluoroethan-1-one (CAS 270584-80-0) is a high-purity analytical reference standard with the molecular formula C6H9F3N2O and a molecular weight of 182.14 g/mol.

The molecular framework of (R)-1-(3-aminopyrrolidin-1-yl)-2,2,2-trifluoroethan-1-one (C6H9F3N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-1-(3-aminopyrrolidin-1-yl)-2,2,2-trifluoroethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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