1,2,3,4,5-Pentafluoro-6-(2,2,2-trifluoroethyl)benzene CAS 27059-24-1
| CAS No. | 27059-24-1 |
| Molecular Formula | C8H2F8 |
| Molecular Weight | 250.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,2,3,4,5-Pentafluoro-6-(2,2,2-trifluoroethyl)benzene (CAS 27059-24-1) is a high-purity analytical reference standard with the molecular formula C8H2F8 and a molecular weight of 250.09 g/mol.
The molecular framework of 1,2,3,4,5-Pentafluoro-6-(2,2,2-trifluoroethyl)benzene (C8H2F8) is characterized by fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H2F8 |
| Molecular Weight | 250.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
Related Pentafluoro Standards
- 1,2,3,4,5-Pentafluoro-6-(trifluoromethoxy)benzene (CAS 6161-54-2)
- (R)-1-(3-(Pentafluoro-l6-sulfaneyl)phenyl)ethan-1-amine (CAS 2755677-30-4)
- (S)-1-(3-(Pentafluoro-l6-sulfaneyl)phenyl)ethan-1-amine (CAS 2517734-25-5)
- 4-(Pentafluoro-lambda6-sulfanyl)benzamide (CAS 1020113-65-8)
- 3-(Pentafluoro-lambda6-sulfanyl)benzamide (CAS 1240257-83-3)
- 3-Methyl-5-(pentafluoro-lambda6-sulfanyl)benzaldehyde (CAS 1240257-01-5)
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- 1-(3-(Pentafluoro-lambda6-sulfanyl)phenyl)ethan-1-one (CAS 159896-31-8)
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