1,4-bis(3-chloropropyl)piperazine CAS 27145-02-4
| CAS No. | 27145-02-4 |
| Molecular Formula | C10H20Cl2N2 |
| Molecular Weight | 239.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,4-bis(3-chloropropyl)piperazine.
1,4-bis(3-chloropropyl)piperazine (CAS 27145-02-4), molecular formula C10H20Cl2N2 and molecular weight 239.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1,4-bis(3-chloropropyl)piperazine (C10H20Cl2N2) contains chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 239.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,4-bis(3-chloropropyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H20Cl2N2 |
| Molecular Weight | 239.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related bis Standards
- 3-Chloropropyl-n-octylsulfoxide (CAS 3569-57-1)
- 1-(3-chloropropyl)-4-phenylpiperazine (CAS 10599-17-4)
- 1-((3-Chloropropyl)sulfonyl)-4-methylpiperazine (CAS 261767-18-4)
- (3-((3-Chloropropyl)carbamoyl)phenyl)boronic acid (CAS 874288-10-5)
- (4-((3-Chloropropyl)carbamoyl)phenyl)boronic acid (CAS 874460-03-4)
- 2-(3-Chloropropyl)-6-methoxyquinazoline (CAS 2006276-98-6)
- 6-(3-Chloropropyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 1272758-37-8)
- Ethyl 4-(3-chloropropyl)piperazine-1-carboxylate (CAS 74571-66-7)
Recommended Standards
- Ethyl 2-(trifluoroacetyl)-3-(N,N-dimethylamino)-2-propenoate (CAS 267243-86-7)
- 3-(6-Fluoro-2,3-dihydro-3-oxobenzo[b][1,4]oxazin-4-yl)propanoic Acid (CAS 1065678-56-9)
- Aciclovir Impurity 6 (CAS 80685-22-9)
- 2-(4-(Trifluoromethyl)phenyl)pyrimidin-5-amine (CAS 1094311-67-7)
- Benzyl (S)-5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide (CAS 1489246-88-9)
- 2-Bromo-6-(difluoromethyl)-4-methoxy-3-(trifluoromethyl)pyridine (CAS 1806869-88-4)
- 1-(Pyrazin-2-ylmethyl)pyrrolidin-3-amine (CAS 1251222-69-1)
- 2-Bromo-1,4-dioxane (CAS 179690-41-6)
- Methyl 1-[2-(hydroxymethyl)phenyl]-5-methyl-1H-pyrazole-3-carboxylate (CAS 1251950-60-3)
- Poly[9,9-bis[3-(dimethylamino)propyl]-9′,9′-dioctyl[2,2′-bi-9H-fluorene]-7,7′-diyl], compd. with bromoethane (CAS 673474-77-6)
- Cyclopentyl(cyclopropyl)methanone (CAS 58774-11-1)
- N5-((R)-3-(((R)-2-((S)-4-amino-4-carboxybutanamido)-2-carboxyethyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine (CAS 90663-73-3)
- O-((3-Methylisoxazol-5-yl)methyl)hydroxylamine (CAS 238760-87-7)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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