4,5-Di-tert-butyl-1H-imidazole CAS 2718-16-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2718-16-3
Molecular FormulaC11H20N2
Molecular Weight180.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,5-Di-tert-butyl-1H-imidazole CAS 2718-16-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,5-Di-tert-butyl-1H-imidazole.

4,5-Di-tert-butyl-1H-imidazole (CAS 2718-16-3) is a high-purity analytical reference standard with the molecular formula C11H20N2 and a molecular weight of 180.29 g/mol.

The molecular framework of 4,5-Di-tert-butyl-1H-imidazole (C11H20N2) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4,5-Di-tert-butyl-1H-imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H20N2
Molecular Weight180.29 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957
Nitrogen Atoms2

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