2,3-Bis(chloromethyl)pyridine hydrochloride CAS 27221-49-4
| CAS No. | 27221-49-4 |
| Molecular Formula | C7H7Cl2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,3-Bis(chloromethyl)pyridine hydrochloride (CAS 27221-49-4) is a high-purity analytical reference standard with the molecular formula C7H7Cl2NHCl and a molecular weight of 212.50 g/mol.
Owing to a nitrile group, chlorine substitution, 2,3-Bis(chloromethyl)pyridine hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 212.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2,3-Bis(chloromethyl)pyridine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7Cl2N HCl |
| Molecular Weight | 212.50 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
- 7-(Chloromethyl)-2,3-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-82-5)
- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 5-(Chloromethyl)-7-ethoxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1000932-47-7)
- 5-(chloromethyl)-N-(4-fluorobenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-60-4)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- Sodium 3-(3-(trifluoromethyl)phenyl)propanoate (CAS 1260665-39-1)
- 3-(4-Ethoxyphenyl)-1,2-oxazol-5-ol (CAS 1354920-17-4)
- 3,4-Diamino-2-(trifluoromethyl)pyridine (CAS 1227581-91-0)
- Lornoxicam-D4 (CAS 1216527-48-8)
- (5R,5R)-Dihydroxy Lysinonorleucine (CAS 869111-52-4)
- 5-Chloropentylzinc bromide 0.5 M in Tetrahydrofuran (CAS 312624-21-8)
- 1-Dodecanol (CAS 112-53-8)
- 2,3-Dibromopropene (CAS 513-31-5)
- 2-((4-Ethyl-5-(((6-oxo-1-phenyl-1,6-dihydropyridazin-3-yl)oxy)methyl)-4H-1,2,4-triazol-3-yl)thio)-N-phenylacetamide (CAS 439112-32-0)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
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