3-chloro-5-methyl-5H-Pyridazino[3,4-b][1,4]benzoxazine CAS 27225-84-9
| CAS No. | 27225-84-9 |
| Molecular Formula | C11H8ClN3O |
| Molecular Weight | 233.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-chloro-5-methyl-5H-Pyridazino[3,4-b][1,4]benzoxazine.
3-chloro-5-methyl-5H-Pyridazino[3,4-b][1,4]benzoxazine (CAS 27225-84-9), molecular formula C11H8ClN3O and molecular weight 233.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-chloro-5-methyl-5H-Pyridazino[3,4-b][1,4]benzoxazine (C11H8ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-chloro-5-methyl-5H-Pyridazino[3,4-b][1,4]benzoxazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O |
| Molecular Weight | 233.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
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- 6-Chloro-N-pyridin-4-ylnicotinamide (CAS 1090481-07-4)
- 2-Chloro-5-(pyridin-2-yl)benzoic acid (CAS 1143024-51-4)
- 5-Chloro-6-phenylpyridine-3-carboxylic acid (CAS 1148027-23-9)
- 2-Chloro-5-phenylnicotinic acid (CAS 117449-73-7)
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- 3-Chloro-6-phenylpyridazine-4-carboxamide (CAS 118269-69-5)
- 2-Chloro-5-phenylisonicotinic acid (CAS 1214323-23-5)
Recommended Standards
- 3-Chloro-4'-nitro-1,1'-biphenyl (CAS 952-22-7)
- 3-Chloro-N,N-bis(cyanomethyl)benzamide (CAS 54240-91-4)
- 3-Chloro-3'-nitro-1,1'-biphenyl (CAS 952-04-5)
- 4-(3-CHLOROPYRIDIN-2-YL)BENZOIC ACID (CAS 582325-32-4)
- Dihydrotriazine (CAS 1347860-96-1)
- 3-bromo-1H,1aH,6H,6aH-cyclopropa[a]indene-1-carboxylic acid (CAS 2060042-54-6)
- 3-(4-Chlorophenyl)-2-(o-tolylthio)quinoline (CAS 339013-31-9)
- 2-cyclopropyl-5-methylbenzoic acid (CAS 1525520-64-2)
- Tert-butyl 4-oxo-3-propylpiperidine-1-carboxylate (CAS 277298-22-3)
- N-(2-Ethoxyphenyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepine-7-sulfonamide (CAS 941881-12-5)
- Methyl 3-cyclopropylbenzoate (CAS 148438-02-2)
- 3-(Pent-3-en-1-ylamino)thietane 1,1-dioxide (CAS 1865882-94-5)
- 5-(2-Aminoethyl)-6-hydroxy-1-methylpyrimidin-2(1H)-one (CAS 1142201-84-0)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
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